HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i- – Let's Fibre Technologies
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421
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HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421

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Hp Proliant Dl380 Gen11 4410y 2.0ghz 12-core 1p 32gb-r Mr408i-o Nc 8sff 800w Ps Server P52560-421

Description

HPE P52560-B21 DL380 Gen11 4410Y 1P 32GB-R MR408i-o NC 8SFF 800W PS Server

Adaptable for diverse workloads and environments, the secure 2P 2U HPE ProLiant DL380 Gen11 Server delivers world-class performance with the right balance of expandability and scalability.

The HPE ProLiant DL380 Gen11 is designed for supreme versatility and resiliency while being backed by a comprehensive warranty, makes it ideal for multiple environments from Containers to Cloud to Big Data. Standardize on the industry’s most trusted compute platform.

 

HPE ProLiant DL380 Gen11


 

 

 

 

Front View – 8SFF chassis with optional Universal Media Bay shown

 

Item

Description

Item

Description

1.

Optional Front DisplayPort (via Universal Media Bay)

8.

Power On/Standby button/LED

2.

Box 1 (shown with optional Universal Media Bay installed)

9.

iLO Service Port

3.

Box 2 (Empty)

10.

USB 3.2 Gen1

4.

Quick removal access panel

11.

Box 3 (shown with 8SFF drives populated)

5.

Unit Identification button/LED

12.

Optional USB 2.0 port (via Universal Media Bay)

6.

NIC Status1

13.

Drive Support Label

7.

Health LED

14.

Serial Number Label Pull Tab

Notes: 1 Front NIC LED display doesn’t support NIC LED ACT/LINK indication from ALOM/PCIe/FLOM NICs.

 

 

Front View – 12LFF chassis shown

Item

Description

Item

Description

1.

Quick removal access panel

6.

iLO Service Port

2.

Unit Identification Button/LED

7.

USB 3.2 Gen1 Port

3.

NIC Status

8.

12 x LFF Media

4.

Health LED

9.

Drive support label

5.

Power On/Standby button/LED

10.

Serial Number Label Pull Tab

 


 

 

Front View –12EDSFF chassis shown

Item

Description

Item

Description

1.

12EDSFF drive bays optical drive

7.

iLO Service Port

2.

Quick removal access panel

8.

USB 3.2 Gen1

3.

UID Button/LED

9.

12x EDSFF Media

4.

NIC Status

10.

Drive support label

5.

Health LED

11.

Serial Number Label Pull Tab

6.

Power On/Standby button and LED

 

 

 


 

 

Internal View 8SFF chassis

Item

Description

Item

Description

1.

Hot Plug Fans1

6.

Primary Riser

2.

Processors with heatsinks shown

7.

 DIMM slots, shown fully populated in 32 slots2

3.

Optional NS204i-u Boot Device

8.

Drive Backplanes

4.

Hot Plug redundant HPE Flexible Slot Power Supplies

9.

Drive Cages

5.

Secondary Riser (Optional) (Requires second processor)

 

 

Notes:

- 1High-performance temperature fans optional.

- 2Shown fully populated in 32 slots (16 per processor).


 

 

Rear View – Standard for all DL380 Gen11

Item

Description

Item

Description

1.

Primary Riser. PCIe 5.0 Slots (Slots 1-3)

7.

VGA Connector

2.

OCP NIC 3.0 Slots, shown covered

8.

Serial Port Optional

3.

Secondary Riser. PCIe 5.0 Slots (Slots 4-6)

9.

Dedicated iLO Management Port

4.

Tertiary Riser (Slots 7-8) shown with optional 2SFF drive cage installed

10.

USB 3.2 Gen1 Connectors (2)

5.

Optional NS204i-u Boot Device

11.

UID Indicator LED

6.

Power Supply

 

 

Notes:  1 Supports various NICs, and Storage controllers.

 


Platform Information

 

Form Factor

- 2U rack

Chassis Types

-  8SFF (SAS/SATA/NVMe) with optional 6SFF Universal Media Bay (P50728-B21), and/or up to 6SFF rear drive bay options.

- 24SFF bay (SAS/SATA/NVMe) with up to 6SFF rear drive bay options for a total 30 SFF drives.

- 8LFF supporting 2SFF front, and up to 4LFF rear or 2SFF rear drive bay options.

- 12LFF with optional 4LFF rear for a total of 16LFF drives.

- 12EDSFF (NVMe) supporting up to 36 EDSFF in front and up to 2SFF rear drive bay option.

Notes:

- The 8SFF chassis is upgraded to support up to 24SFF (front) with a variety of 8SFF Drive Cages to select from, including 8SFF U.3 x4/x2 Trimode, 8SFF U.3 (x1 Trimode), and 8SFF SAS/SATA. See "Drive Cages" section within this document for options.

- The 8SFF chassis comes with an 8SFF U.3 x1 Trimode drive bay by default in bay 3.

- The Universal Media Bay (P50728-B21) is only available as an option for the 8SFF chassis and can only be populated in Box 1.

- The 2LFF primary and 2LFF secondary rear cages will consume all PCIe slots for the primary and secondary riser, respectively.

- The 8LFF chassis cannot be upgraded to 12LFF front in the field.

- The 2LFF primary and 2LFF secondary rear cages are supported in LFF chassis only.

System Fans

- High-performance Fan Kit – required for all CPUs over 205W TDP.

Notes:

- On 8SFF CTO server models ship with 4 standard fans.

- The 12LFF and 8LFF CTO server models ship with 4 standard fans.

- The 24SFF CTO server model ships with 6 high-performance fans.

- The High-Performance fan kit (P48820-B21) is available to meet ambient temperature requirements.

- In general, the Maximum Performance fan kit is required when rear drives, or >205W Processors SKUs, or High-performance NVMe drives, three drive cages, mid-tray, GPU card, or certain backplanes are populated. See notes under each option category or each individual option for specifics.

The HPE ProLiant DL380 Gen11 4410Y Server 2.0ghz 12-Core 1p 32GB-R MR408i-O NC 8SFF 800w, designed for supreme versatility and resilience P52560-421 is the yin, to your yang. You've found what you're looking for.

Inventory Last Updated: Sep 05, 2026